diff --git a/.github/workflows/import.yml b/.github/workflows/import.yml
index 08e11ec02f..89cb1a6f50 100644
--- a/.github/workflows/import.yml
+++ b/.github/workflows/import.yml
@@ -13,7 +13,7 @@ jobs:
 
     strategy:
       matrix:
-        python-version: ['3.10', '3.11', '3.12', '3.13', '3.14', '3.15']
+        python-version: ['3.11', '3.12', '3.13', '3.14', '3.15']
 
     steps:
       - name: Checkout repository
diff --git a/.github/workflows/mypy.yml b/.github/workflows/mypy.yml
index 60811d5578..69d7d12c09 100644
--- a/.github/workflows/mypy.yml
+++ b/.github/workflows/mypy.yml
@@ -17,7 +17,7 @@ jobs:
     runs-on: ubuntu-latest
     strategy:
       matrix:
-        python-version: ['3.10', '3.11', '3.12', '3.13', '3.14', '3.15']
+        python-version: ['3.11', '3.12', '3.13', '3.14', '3.15']
 
     steps:
       - name: Checkout code
diff --git a/pyproject.toml b/pyproject.toml
index d0396e651d..21c03645a4 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -7,7 +7,7 @@ version = "2.33.0"
 description = "GenAI Python SDK"
 readme = "README.md"
 license = "Apache-2.0"
-requires-python = ">=3.10"
+requires-python = ">=3.11"
 authors = [
     { name = "Google LLC", email = "googleapis-packages@google.com" },
 ]
@@ -16,7 +16,6 @@ classifiers = [
     "Operating System :: OS Independent",
     "Programming Language :: Python",
     "Programming Language :: Python :: 3",
-    "Programming Language :: Python :: 3.10",
     "Programming Language :: Python :: 3.11",
     "Programming Language :: Python :: 3.12",
     "Programming Language :: Python :: 3.13",
diff --git a/requirements.txt b/requirements.txt
index 2453ad31d4..cb445a2662 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -7,7 +7,7 @@ charset-normalizer==3.4.0
 coverage==7.6.9
 distro==1.9.0
 httpx==0.28.1
-httpx2==2.7.0; python_version >= '3.10'
+httpx2==2.7.0
 google-auth==2.56.0
 idna==3.18
 iniconfig==2.0.0
@@ -33,6 +33,6 @@ tenacity==8.2.3
 typing_extensions>=4.14.1
 urllib3==2.5.0
 websockets==16.0
-mcp>=1.14.0,<2.0.0; python_version > '3.9'
+mcp>=1.14.0,<2.0.0
 sentencepiece>=0.2.0; python_version < '3.15'
 protobuf